… reorganization and disrupts epithelial barrier integrity 100 4.1. … of protein toxins that enter
mammalian cells and covalently modify … Clostridium sordellii lethal toxin kills mice by inducing a …

… , and likely to change these through DNA recombination. … , increasing the permeability of
epithelial and endothelial cells (both … are unable to cross the blood–brain barrier. However, the …

… the intestinal barrier without significant alteration of intestinal cells, transits in … intercellular
junctions, morphological changes of intestinal … sordellii (previously Clostridium sordellii) toxins (…

… specifically inhibited by Clostridium sordellii lethal toxin (LT). … to increased vascular
permeability, tissue edema and death … were not mediated by a change in cholesterol levels, we …

… tors have an impact on the permeability of the outer membrane barrier function: (I… toxin
family such as Clostridium sordellii lethal toxin possess a different substrate specificity and modify …

… of host cells to form a pore, thus disrupting cell barriers and … on epithelial cells causes a
conformational change, allowing … permeability to protons and subsequently intracellular ions …

… toxic chemicals and bacterial toxins that contribute to barrier … of host chaperons; IV, modification
of target substrates (GTD, … epithelial renewal, increasing colonic vascular permeability, …

… , producing an increased paracellular permeability in cultured intestinal cells in vitro [Citation…
the exposure of toxin receptors on the host cell surface and/or NanI modifying the host …

… , two former Clostridium species, that is, Clostridium sordellii (… the tight junctions of intercellular
barrier without causing … including slurred speech; any change in sound of voice including …

… toxin induces elevation of intestinal permeability which is accompanied by a histological
change in the intestinal epithelia… By itself, μ-toxin is a nonlethal toxin but it is thought to …